Cigarette Smoking Man: Leaves me to tell you what Mulder's afraid to, Agent Scully.
Mulder: Come on, let's go.
Cigarette Smoking Man: It's a scary story. Want to come sit on my lap?
Scully: You don't scare me.
Cigarette Smoking Man: My story's scared every president since Truman in '47.
Mulder: [To Scully] You don't have to hear this.
Scully: No, I wanna hear it, Mulder.
Cigarette Smoking Man: Ten centuries ago the Mayans were so afraid that their calendar stopped on the exact date that my story begins. December 22, the year 2012. The date of the final alien invasion. Mulder can confirm the date. He saw it at Mount Weather... where our own 'Secret Government' will be hiding when it all comes down.
Mulder: Yeah, you smile... feeling drunk with power. The power to do nothing.
Cigarette Smoking Man: My power comes from telling you. Seeing your powerlessness hearing it. They wanted to kill you, Fox. I protected you all these years... waiting for this moment... to see you broken. Afraid. Now you can die.

Frohike: [Mulder is urinating at the roadside] Hey hotshot. Might have the common courtesy of doing your little business downwind.
Mulder: Oh boy.
Langly: Why don't you finish draining the little lizard then we'll talk?
Byers: We're very worried about you.
Frohike: It's craziness, man. Turn around.
Langly: Just hang a big U-ie and never look back.
Mulder: I can't.
Byers: Why risk perfect happiness, Mulder? Why risk your lives?
Mulder: Because I need to know the truth.
Byers: You already know the truth.
Mulder: I need to know if I can change it.
Langly: Change it?
Frohike: For crying out loud. All you're going to do is get yourself killed.
Scully: Mulder! What are you doing?
Mulder: [The Lone Gunmen have vanished] I'll be right with you, Scully.

Doggett: [answering phone] Yeah... I'll tell her. [He hangs up]
Scully: Who was it?
Doggett: Skinner.
Scully: Agent Doggett?
Doggett: Death by lethal injection.

Reyes: What is the point of all of this? To destroy a man who seeks the truth, or to destroy the truth so no man can seek it? Either way, you lose.

Scully: Mulder. Mulder!
Mulder: I smelled you coming, Clarice.
Scully: Oh... Damn it, Mulder. It's not funny to see you putting on that act.
Mulder: No, that is funny. What's not funny is what they do to you in here if you don't put on that act. [They embrace, Skinner averts his eyes allowing them a little privacy] Come here, you big, bald, beautiful man.
Skinner: The only thing you're going to be kissing, Mulder, is your sweet ass good-bye, with the trouble your in.
Mulder: Uh-huh, I kind of gathered that, right around the 50th brainwashing session. (he kisses Scully on the hand)
Scully: Mulder, why are they doing this to you?
Mulder: They think they're preparing me for my trial. For my testimony.

Guard: What are you thinking?
Mulder: About my son... about his mother.
Guard: Wrong answer! [He swings at Mulder and misses] What are you thinking?
Mulder: What do you want from me?!
Guard: Wrong... answer! [He swings at Mulder again, they grapple before the guard throttles Mulder with his baton] I want answers, you hear me? I want answers! [He leaves]

Guard: What are you thinking?
Mulder: Where am I?
Guard: Wrong answer! What are you thinking?
Mulder: I'm thinking about getting the hell out of here.
Guard: Wrong... answer! [He hits Mulder and walks to the door of the cell] No sleeping!

Mulder: [After escaping Knowle Rohrer with help from Krycek's ghost] No! You're dead!
Krycek: Go. There's others. [An alarm rings & Krycek vanishes]

Doggett: So close, Dana. I'm sorry you don't get your proof.
Scully: Me too. Well, maybe I've had it these past nine years. If not proof of the paranormal, then... of more important things. (looks at Oliver for a moment, then leaves)
Doggett: Well, here's hopin' the TV stays off and he learns how to love the real world.
Reyes: (smiles and takes his hand) I think you are getting the hang of this job.

Doggett: Okay, so be it. Just tell me how this helps me bust him, and uh, I'm happy.
Scully: Well, I'm starting to hope that it doesn't come to that.
Reyes: What do you mean?
Scully: Well, the power that this man seemingly possesses is extraordinary. It needs to be studied.
Dr Reits: It could expand the scope of human knowledge. It could change everything.
Scully: It very well could. I mean, I've... I've been working this unit for nine years now. I-I've investigated nearly 200 paranormal cases. We are due for some incontrovertible proof. I want vindication, for... for Mulder and... for all of us.