The Ten Commandments Nefretiri: I saved your son.
Moses: It is not my son who will die, it is the first born of Egypt, it is your son, Nefretiri!
Nefretiri: You would not dare strike Pharaoh's son!
Moses: In the hardness of his heart, Pharaoh has mocked God and brings death to his own son!
Nefretiri: But he is my son. You would not kill my son.
Moses: Without God I am nothing. I am the tool by which he works his will.
Nefretiri: But I saved your son!
Moses: I cannot save yours.

Red vs Blue Grif: [Suprised by nearby explosion] Son of a bitch!
Simmons: Son of a bitch!
Church: [Possessing Lopez] Madre de Dios! [Translated as 'Mother of God']

Anne Rice What I did was take the Jesus of the Gospels, the Son of God, the Son of the Virgin Mary, and sought to make Him utterly believable, a vital breathing character.

Oz Alvarez: Father, where was God when my son died?
Mukada: Same place He was when His own son died.

David Icke Everyone is a son or daughter of god.

Shoot 'Em Up (upon seeing he ran over a robotic decoy of Oliver) What in the hell is that? Oh, my God, that is twisted. That sick son of a bitch. That sick son of a bitch suckered us again!

X2 X-men 2 Professor Charles Xavier: Oh, my god, William, this is your son! What have you-
Colonel William Stryker: NO, Charles! My son is dead! Just like the rest of you.

Beavis and Butthead Do America Beavis: [in time with the song] Damn it, damn it, son of a bitch. Damn it, damn it, son of a bitch.
Butt-head: If those were the words, it'd be cool!
Beavis: I was thinking of writing a song called "Damn it, Son of a bitch!" And it's gonna go something like "Damn it, damn it, son of a bitch/Damn it, damn it, son of a bitch/Son of a BIIIITTTCCCHHHH!/SON OF A BITCH, SON OF A BITTTCCHHH!/Dammit dammit dammit".
Butt-head: That's pretty cool.

Goodness Gracious Me Son: I'm gay, OK?
Simon: And so am I.
Father: What, BOTH of you?!
Mother: Oh, my God! My son is a lesbian!
Father: You go to your room, and don't come back until you're not of the gay!

Looney Tunes Show, The [after smacking his thumb with a hammer] Oh, son of a bi-bi-, son of a bi-bi-, son of a bi-bi-bi-...gun! [turns to the camera] Ha-ha-ha! You thought I was going to say 's-s-son of a bitch', didn't ya?!