Battlestar Galactica 2003 [The first Hybrid and Shaw, just before Shaw detonates the nuclear warhead]
The first Hybrid: As my own existence comes to a close, only to begin anew, in ways uncertain.
Shaw: You're scared, aren't you, mother-frakker? You should be.
The first Hybrid: All this has happened before, and it will happen again...again...again...again...again...again...again...again...again

Survivor by Chuck Palahniuk "The truth is you can be orphaned again and again and again.

Fruits Basket Just as no matter how hard you try to keep it away... despair will attack you again and again. In the same manner hope will return to you. Again and again.

Sonny Terry So I went out and bought Hard Again by Muddy Waters. That was a big learning curve. I listened to that album again and again and again. James Cotton was the harmonica player on that album.

Supernatural Curtis: They did tests on me, and um…[he takes a shot] –- they, uh…they probed me. [DEAN and SAM try not to laugh.]
Dean: They probed you?
Curtis: Yeah. They probed me. Again and again and again and –- [takes a shot] –- and again and again and again and then one more time.
Dean: [deadpan] Yikes.

Ren amp Stimpy Show, The Admeet eet, waseent that beauteeful? Poignant! Touching!...All right, so eet was eencredibly heedious! But eef you don't send us more cash, we'll show heem again and again and again!"

Justice League [Joker sings to the tune of "London Bridge"]
Joker: (punches Batman) Big old Bats in falling down. (punches him again) on the ground. (again) Mind unsound. (again) Big old Bats is falling down (again) I'm so happy.

Garrison Keillor A book is a gift you can open again and again.

Winston Churchill No comment" is a splendid expression. I am using it again and again.

Ed, Edd, 'n Eddy Eddy: Let's hit 'em again, lug nut!
Ed: Hit 'em again, hit 'em again, hit 'em again! Ha ha ha! I forgot what I said! Ha ha!